Jacksonville (5-8) was led by Dylan Fritsch’s 15 points.
Indiana is 10-0 at Assembly Hall this season. Its closest game was an 83-59 win over North Carolina in early December.
IU got off to another slow start. Jacksonville led 13-11 after seven minutes before the Hoosiers began to assert control.
Hulls was the catalyst. He hit two free throws before going on a three-point shooting onslaught that quickly gave the Hoosiers a double-digit lead.
By halftime, IU led 48-33. Ferrell was impressive with six points, six assists, no turnovers and two steals.
The Hoosiers open Big Ten play at Iowa on Monday.