Deputy Fire Chief Bret Granger says the warehouse was previously a piano factory.
The Star Press reports that in recent years the building has been used by a pallet and skid manufacturer and as a chemical distributor.
A neighbor says he heard explosions inside the building. Firefighters monitored a nearby trailer they say contained oil products.
Property tax records identify the owner as Fochtman Brothers LLC, Berlin, Pennsylvania. A phone number in the company's name was disconnected.