Notre Dame has eliminated Duke from the tournament each of the past two seasons, including a semifinal victory in 2015 on the way to the Irish's first conference tournament championship.
Dwayne Bacon led Florida State (25-8) with 18 points.
The Irish and Seminoles had a tough act to follow after Duke and North Carolina had the sellout crowd of 18,109 rocking in Brooklyn.
Many fans dressed in blue bailed for the nightcap. Not New Jersey Gov. Chris Christie, who was back at Barclays for a second straight night, sitting behind the Notre Dame bench rooting on his buddy, Irish coach Mike Brey.
Notre Dame eliminated most of the drama with a 23-8 run to end the first half that put the Irish up 42-26.
Florida State had the lead down to eight thanks to Braian Angola-Rodas, who scored 14 of the Seminoles' 15 points in one stretch, including a 3-pointer that made it 63-55 with 8:23 left in the second half.
A driving hoop by Vasturia and a hustle putback by Colson nudged the lead back to 12 a little more than a minute later.
Notre Dame: The Irish have thrived with their small lineup, featuring the 6-foot-5 Colson at center. It puts shooters everywhere on the floor and presents matchup problems for bigger teams — such as Florida State. It also helps Notre Dame overcome getting outrebounded as they were by the Seminoles, 41-23.
Florida State: Even though Florida State held a rebounding edge, it didn't do enough damage on the offensive boards. After getting 18 offensive rebounds against Virginia Tech in the quarterfinals, Florida State had nine against the Irish for only eight second-chance points.
Notre Dame: The Fighting Irish lost their only meeting with Duke this season, but Brey is 5-3 in his career against his former boss, Duke coach Mike Krzyzewski.
Florida State: The Seminoles will wait for Selection Sunday to find out their next opponent. They'll probably be a 3 seed.